HIGH COMPLEXITY MICROCOMPARTMENT-BASED INTERACTION SCREENING

The invention regards a method for screening for interactions between two compounds provided in libraries. The invention in particular provides a method for screening interactions, such as a binding between two molecules or macromolecules, that is not limited to a classical screening by bait and pre...

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Bibliographische Detailangaben
Hauptverfasser: Merten, Christoph, Seah, Yu Fen Samantha, Heinis, Christian, Kolmar, Leonie, Autour, Alexis Louis, Mei, Anna
Format: Patent
Sprache:eng
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Zusammenfassung:The invention regards a method for screening for interactions between two compounds provided in libraries. The invention in particular provides a method for screening interactions, such as a binding between two molecules or macromolecules, that is not limited to a classical screening by bait and prey setup, and therefore allows for a high-complexity screening of large candidate libraries, including screening for immunological interactions such as interactions between T-cells and antigen presenting cells, or B-cells and their antigenic targets.