PHOSPHOLIPIDS AS ANION CHELATING AGENTS IN PHARMACEUTICAL FORMULATIONS

Disclosed herein are dosage forms including a fill material that incorporates an anionic chelating agent, such as lecithin, and a salt form of a basic or acidic active pharmaceutical ingredient and a free ion. The molar ratio of the anionic chelating agent, such as lecithin, to the free ion ranging...

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Hauptverfasser:	Au, Giang Hoang Thuy, Bush, William Derek
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	Au, Giang Hoang Thuy Bush, William Derek
description	Disclosed herein are dosage forms including a fill material that incorporates an anionic chelating agent, such as lecithin, and a salt form of a basic or acidic active pharmaceutical ingredient and a free ion. The molar ratio of the anionic chelating agent, such as lecithin, to the free ion ranging from about 0.5 to about 3. Also disclosed herein are methods of stabilizing dosage forms that include a salt form of a basic or acidic active pharmaceutical ingredient, methods of preparing such dosage forms, and methods of using such dosage forms.
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The molar ratio of the anionic chelating agent, such as lecithin, to the free ion ranging from about 0.5 to about 3. 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subjects	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	PHOSPHOLIPIDS AS ANION CHELATING AGENTS IN PHARMACEUTICAL FORMULATIONS
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