LIQUID PHARMACEUTICAL COMPOSITIONS OF BACLOFEN FOR ORAL ADMINISTRATION

Liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof are described. More specifically, stable liquid pharmaceutical compositions of baclofen at concentrations of 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions are suitable for...

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Hauptverfasser: Pattewar, Purushottam Sakhahari, Saoji, Suprit Dilip, Pawar, Abhijit Balaji, Subbappa, Praveen Kumar, Dube, Sushant Omprakash, Kore, Girish G, Chatki, Pankaj Kisan, Pillai, Sumitra Ashokkumar
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creator Pattewar, Purushottam Sakhahari
Saoji, Suprit Dilip
Pawar, Abhijit Balaji
Subbappa, Praveen Kumar
Dube, Sushant Omprakash
Kore, Girish G
Chatki, Pankaj Kisan
Pillai, Sumitra Ashokkumar
description Liquid pharmaceutical compositions of baclofen or a pharmaceutically acceptable salt thereof are described. More specifically, stable liquid pharmaceutical compositions of baclofen at concentrations of 2 mg/mL or more are provided. Preferably, the liquid pharmaceutical compositions are suitable for oral administration, and stable at pH ranges of 3-8 over a variety of storage conditions, including long-term storage for extended periods of time. Various methods for preparing stable liquid pharmaceutical compositions of baclofen are described. Methods of treating spasticity using the inventive pharmaceutical compositions are also provided.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title LIQUID PHARMACEUTICAL COMPOSITIONS OF BACLOFEN FOR ORAL ADMINISTRATION
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