INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE

Disclosed are compounds of Formula (I)pharmaceutically acceptable salts thereof are defined herein, and pharmaceutical compositions thereof and combinations thereof, and methods of using the same as inhibitors of protein tyrosine phosphatases (PTPN2). These compounds are useful in treating cancer an...

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Hauptverfasser: BRONSON, JOANNE JEWETT, PENDRI, ANNAPURNA, LIU, HAIBO, D'AGOSTINO, LAURA AKULLIAN, POSY, SHOSHANA L, MU, YUCHENG
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creator BRONSON, JOANNE JEWETT
PENDRI, ANNAPURNA
LIU, HAIBO
D'AGOSTINO, LAURA AKULLIAN
POSY, SHOSHANA L
MU, YUCHENG
description Disclosed are compounds of Formula (I)pharmaceutically acceptable salts thereof are defined herein, and pharmaceutical compositions thereof and combinations thereof, and methods of using the same as inhibitors of protein tyrosine phosphatases (PTPN2). These compounds are useful in treating cancer and diseases susceptible to PTPN2 inhibition.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE
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