BIOMARKER FOR PREDICTING RESPONSIVENESS TO ANTICANCER AGENT AND USE THEREOF

The present invention relates to a biomarker for predicting responsiveness to an anticancer agent and a use thereof, and more particularly, to: a marker composition for predicting responsiveness to atezolizumab, avelumab, or durvalumab, the marker composition comprising at least one gene selected fr...

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Hauptverfasser: LEE, Jee Yun, KIM, Kyoung Mee
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creator LEE, Jee Yun
KIM, Kyoung Mee
description The present invention relates to a biomarker for predicting responsiveness to an anticancer agent and a use thereof, and more particularly, to: a marker composition for predicting responsiveness to atezolizumab, avelumab, or durvalumab, the marker composition comprising at least one gene selected from the group consisting of armadillo repeat-containing X-linked protein 1 (ARMCX1), serine/threonine-protein kinase D1 (PRKD1), and tyrosine kinase 2 (TYK2), or protein(s) encoded by the at least one gene; a composition for predicting responsiveness; a kit comprising the composition; and a method for providing information for predicting responsiveness. Gene markers according to the present invention are analyzed using patient-derived formalin-fixed paraffin-embedded tissues, and thus do not require the separate collection of samples, and the therefore convenient to analyze.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
title BIOMARKER FOR PREDICTING RESPONSIVENESS TO ANTICANCER AGENT AND USE THEREOF
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