T CELLS MODIFIED TO EXPRESS MUTATED CXCR4 OR PARTIALLY DELETED AND USES THEREOF

The present invention relates to modified T cells, and in particular to CD8 T cells, for use in therapy. The current inventors investigates the effect of CXCR4Whim mutation on CD8 effector and memory responses. By analysing the lymphoid organs, including the BM compartment, in a mouse model of Whim...

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Bibliographische Detailangaben
Hauptverfasser: WENCKER, Mélanie, DJEBALI, Sophia, BALABANIAN, Karl, MARVEL, Jacqueline
Format: Patent
Sprache:eng
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