ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF

Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein-1 (hPD-1), and immunoconjugates comprising the same.

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Hauptverfasser:	AYTON, Paul, DOYLE, Anthony Gerard, YAP, Kim Tran, SURADE, Sachin Badrinath, SEN, Debasish, ROZENFELD, Julia, WILSON, JR., David S
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
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creator	AYTON, Paul DOYLE, Anthony Gerard YAP, Kim Tran SURADE, Sachin Badrinath SEN, Debasish ROZENFELD, Julia WILSON, JR., David S
description	Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein-1 (hPD-1), and immunoconjugates comprising the same.
format	Patent
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subjects	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
title	ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF
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