MUTANT G-PROTEIN COUPLED RECEPTORS AND METHODS FOR SELECTING THEM

The invention relates to mutant G-protein coupled receptors with increased conformational stability, and methods of use thereof. In some aspects, polynucleotides encoding the mutant G-protein coupled receptors are provided. In some aspects, host cells comprising the polynucleotides are provided. In...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Warne, Antony Johannes, Serrano-Vega, Maria Josefa, Henderson, Richard, Weir, Malcolm Peter, Magnani, Francesca, Tate, Christopher Gordon, Shibata, Yoko
Format: Patent
Sprache:eng
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