QUINAZOLINE PAN-KRas INHIBITORS
The present invention relates to compounds that inhibit at least one of KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
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| creator | Smith, Christopher Ronald Wang, Xiaolun Lawson, John David Ivetac, Anthony Marx, Matthew Arnold Kulyk, Svitlana |
| description | The present invention relates to compounds that inhibit at least one of KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor. |
| format | Patent |
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HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240125&DB=EPODOC&CC=US&NR=2024025907A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240125&DB=EPODOC&CC=US&NR=2024025907A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Smith, Christopher Ronald</creatorcontrib><creatorcontrib>Wang, Xiaolun</creatorcontrib><creatorcontrib>Lawson, John David</creatorcontrib><creatorcontrib>Ivetac, Anthony</creatorcontrib><creatorcontrib>Marx, Matthew Arnold</creatorcontrib><creatorcontrib>Kulyk, Svitlana</creatorcontrib><title>QUINAZOLINE PAN-KRas INHIBITORS</title><description>The present invention relates to compounds that inhibit at least one of KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAPDPX0c4zy9_H0c1UIcPTT9Q5KLFbw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgZGJgZGppYG5o6GxsSpAgCKOiL_</recordid><startdate>20240125</startdate><enddate>20240125</enddate><creator>Smith, Christopher Ronald</creator><creator>Wang, Xiaolun</creator><creator>Lawson, John David</creator><creator>Ivetac, Anthony</creator><creator>Marx, Matthew Arnold</creator><creator>Kulyk, Svitlana</creator><scope>EVB</scope></search><sort><creationdate>20240125</creationdate><title>QUINAZOLINE PAN-KRas INHIBITORS</title><author>Smith, Christopher Ronald ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | QUINAZOLINE PAN-KRas INHIBITORS |
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