METHODS FOR TREATING OR PREVENTING ACUTE RESPIRATORY DISTRESS SYNDROME

The present disclosure relates to methods of treating or preventing acute respiratory distress syndrome (ARDS) using compounds that bind to CD131 and neutralize signaling by IL-3, IL-5 and GM-CSF. The present disclosure also relates to compounds for use in the treatment or prevention of ARDS, as wel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOZINOVSKI, Steven, CAMPBELL, Ian Keith, KRSTEVSKI, Karolina, LOPEZ, Angel Francisco, TUMES, Damon John, OWCZAREK, Catherine Mary
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure relates to methods of treating or preventing acute respiratory distress syndrome (ARDS) using compounds that bind to CD131 and neutralize signaling by IL-3, IL-5 and GM-CSF. The present disclosure also relates to compounds for use in the treatment or prevention of ARDS, as well as the use of such compounds in the manufacture of medicaments for the treatment or prevention of ARDS.