CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA

Provided are compounds of the Formula (I), or their pharmaceutically acceptable salts, wherein X1, X2, X3, A1, A2, R1-R7, R8a, R8b, R9a, R9b, R10 and R11 are as herein described.can trap IL-1β and are expected to have utility as therapeutic agents, for example, for treating cardiovascular disease an...

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Hauptverfasser:	Hanisak, Jennifer, Jayne, Charles Lee, Feng, Danqing, Guo, Zhuyan, Plummer, Christopher W, Kekec, Ahmet, Hickey, Jennifer L, Pavone, Francesca, Colarusso, Stefania, Lo, Michael Man-Chu, Nizi, Emanuela, Yousif, Ali Munaim, Bianchi, Elisabetta, Cruz, Faben A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
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