COMPOSITION AND METHOD FOR TREATING CANCER

A new use of estrogen-related receptor γ (ERRγ) inhibitor in enhancing cancer treatment and a pharmaceutical composition for inhibiting the resistance of cancer to tyrosine kinase inhibitors and enhancing an anticancer effect are disclosed. The pharmaceutical composition contains an ERRγ inhibitor a...

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Bibliographische Detailangaben
Hauptverfasser:	Jeon, Yong Hyun, Lee, Do Hyun, Cho, Sung Jin, Park, Keun Gyu, Lee, In Kyu, Kim, Mi Jin, Jung, Hoe Yune, Choi, Yeon Kyung, Chin, Jung Wook, Kim, Jin A, Kim, Dong Su
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A new use of estrogen-related receptor γ (ERRγ) inhibitor in enhancing cancer treatment and a pharmaceutical composition for inhibiting the resistance of cancer to tyrosine kinase inhibitors and enhancing an anticancer effect are disclosed. The pharmaceutical composition contains an ERRγ inhibitor as an active ingredient. The pharmaceutical composition for treating tyrosine kinase inhibitor-resistant advanced cancer. The composition can be administered in combination with tyrosine kinase inhibitor. A method for determining if a cancer is tyrosine kinase-resistant is also disclosed.