ENGINEERED FIBRILLAR EXTRACELLULAR MATRIX NETWORKS FOR THREE-DIMENSIONAL (3D) CELLULAR SUPPORT SYSTEMS

ENGINEERED FIBRILLAR EXTRACELLULAR MATRIX NETWORKS FOR THREE-DIMENSIONAL (3D) CELLULAR SUPPORT SYSTEMS

Synthetic cellular support systems in the form of engineered extracellular matrices are provided. The cellular support system may include a three-dimensional scaffold structure comprising at least one void. At least one suspended fibril spans across the at least one void in the three-dimensional sca...

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Hauptverfasser: WAWRYSZYN, Mirella, LAHANN, Joerg, NEALE, Dylan B
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BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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creator WAWRYSZYN, Mirella
LAHANN, Joerg
NEALE, Dylan B
description Synthetic cellular support systems in the form of engineered extracellular matrices are provided. The cellular support system may include a three-dimensional scaffold structure comprising at least one void. At least one suspended fibril spans across the at least one void in the three-dimensional scaffold structure. The suspended fibril comprises at least one extracellular matrix protein, such as fibronectin, and at least one glycan, such as a hyaluronic acid. The suspended fibril is capable of supporting cells and promoting three-dimensional cellular growth. In various aspects, a plurality of suspended fibrils may span the void to form a three-dimensional suspended fibrillar network.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title ENGINEERED FIBRILLAR EXTRACELLULAR MATRIX NETWORKS FOR THREE-DIMENSIONAL (3D) CELLULAR SUPPORT SYSTEMS
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