COMPOSITIONS OF SARS-COV-2 VACCINES BASED ON THE RECEPTOR BINDING DOMAIN, EXPRESSED AS A DIMER, AND THE OUTER MEMBRANE VESICLE OF MENINGOCOCCAL GROUP B BACTERIA

This invention is related to biotechnology; in particular, to the field of human health. The described vaccine compositions induce a neutralizing immune response against the SARS-CoV-2 virus. These compositions include a portion of the receptor binding protein of the SARS-Cov-2 virus, as antigen, ou...

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Hauptverfasser: Chovel Cuervo, Mario Landys, Ojito Magaz, Eduardo, Boggiano Ayo, Tammy, García Rivera, Dagmar, Climent Ruiz, Yanet, Valdés Balbín, Yury, Ramírez González, Ubel Jesús, Oliva Hernández, Reynaldo, Pérez Nicado, Rocmira, Rodríguez Noda, Laura Marta, Fernández Castillo, Sonsire, Humberto, González Rodríguez, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo, Chen, Guang Wu
Format: Patent
Sprache:eng
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Zusammenfassung:This invention is related to biotechnology; in particular, to the field of human health. The described vaccine compositions induce a neutralizing immune response against the SARS-CoV-2 virus. These compositions include a portion of the receptor binding protein of the SARS-Cov-2 virus, as antigen, outer-membrane vesicles of the Neisseria meningitides group B bacteria, as immunopotentiating component, and an adjuvant. The vaccine compositions that are described in this invention are useful in the prevention of infection with the SARS-CoV-2 virus.