METHODS, COMPOSITIONS, AND KITS FOR INHIBITING FORMATION OF ADAPTER DIMERS

Methods of reducing adapter-dimers in a sequencing library are provided according to aspects of the present disclosure, including: hybridizing excess 3′ adapters to blocker oligonucleotides forming a hybridized complex, such that the excess 3′ adapters are unavailable to form adapter-dimers, the hyb...

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Bibliographische Detailangaben
Hauptverfasser: Allen, Kevin D, LeBas, Allyson, Gunning, Kerry, Castro, Eric
Format: Patent
Sprache:eng
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