2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

The present invention is directed to certain 2-aminoquinzaoline derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R3, R4, X1, and X2 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Chau, Ryan, Fuller, Peter H, Keylor, Mitchell H, Li, Derun, Acton, III, John J, Yan, Xin, Margrey, Kaila A, Gulati, Anmol, Johnson, Rebecca Elizabeth, Kattar, Solomon, Morriello, Gregori J
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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