Method for Detecting Alpha Fetoprotein Glycoforms by High Resolution Intact Mass Analysis
Methods for identifying and determining an abundance of an alpha fetoprotein (AFP) glycoform in a biological sample includes obtaining a biological sample, separating AFP from the biological sample as an enriched AFP sample, separating intact AFP from the enriched AFP sample, subjecting the intact A...
Gespeichert in:
Hauptverfasser: | , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | Kushnir, Mark M Dunbar, Carmen A Yang, Yifei K |
description | Methods for identifying and determining an abundance of an alpha fetoprotein (AFP) glycoform in a biological sample includes obtaining a biological sample, separating AFP from the biological sample as an enriched AFP sample, separating intact AFP from the enriched AFP sample, subjecting the intact AFP to high resolution mass spectrometry to generate a mass spectrum, identifying at least one AFP glycoform from the mass spectrum, and determining an abundance of the at least one AFP glycoform in the biological from the mass spectrum. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2023296619A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2023296619A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2023296619A13</originalsourceid><addsrcrecordid>eNqNyr0KwjAQAOAuDqK-w4GzYFModAxqrUMXfwanEuO1CcRc6J1D314HH8DpW755dm9RHD2hpxH2KGjFxwF0SM5AjUJpJEEf4RgmS9_0YnhM0PjBwRmZwls8RThFMVagNcygowkTe15ms94ExtXPRbauD9dds8FEHXIyFiNKd7uorSpUVZZ5pfPiv_UBktA7Rw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Method for Detecting Alpha Fetoprotein Glycoforms by High Resolution Intact Mass Analysis</title><source>esp@cenet</source><creator>Kushnir, Mark M ; Dunbar, Carmen A ; Yang, Yifei K</creator><creatorcontrib>Kushnir, Mark M ; Dunbar, Carmen A ; Yang, Yifei K</creatorcontrib><description>Methods for identifying and determining an abundance of an alpha fetoprotein (AFP) glycoform in a biological sample includes obtaining a biological sample, separating AFP from the biological sample as an enriched AFP sample, separating intact AFP from the enriched AFP sample, subjecting the intact AFP to high resolution mass spectrometry to generate a mass spectrum, identifying at least one AFP glycoform from the mass spectrum, and determining an abundance of the at least one AFP glycoform in the biological from the mass spectrum.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230921&DB=EPODOC&CC=US&NR=2023296619A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230921&DB=EPODOC&CC=US&NR=2023296619A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Kushnir, Mark M</creatorcontrib><creatorcontrib>Dunbar, Carmen A</creatorcontrib><creatorcontrib>Yang, Yifei K</creatorcontrib><title>Method for Detecting Alpha Fetoprotein Glycoforms by High Resolution Intact Mass Analysis</title><description>Methods for identifying and determining an abundance of an alpha fetoprotein (AFP) glycoform in a biological sample includes obtaining a biological sample, separating AFP from the biological sample as an enriched AFP sample, separating intact AFP from the enriched AFP sample, subjecting the intact AFP to high resolution mass spectrometry to generate a mass spectrum, identifying at least one AFP glycoform from the mass spectrum, and determining an abundance of the at least one AFP glycoform in the biological from the mass spectrum.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyr0KwjAQAOAuDqK-w4GzYFModAxqrUMXfwanEuO1CcRc6J1D314HH8DpW755dm9RHD2hpxH2KGjFxwF0SM5AjUJpJEEf4RgmS9_0YnhM0PjBwRmZwls8RThFMVagNcygowkTe15ms94ExtXPRbauD9dds8FEHXIyFiNKd7uorSpUVZZ5pfPiv_UBktA7Rw</recordid><startdate>20230921</startdate><enddate>20230921</enddate><creator>Kushnir, Mark M</creator><creator>Dunbar, Carmen A</creator><creator>Yang, Yifei K</creator><scope>EVB</scope></search><sort><creationdate>20230921</creationdate><title>Method for Detecting Alpha Fetoprotein Glycoforms by High Resolution Intact Mass Analysis</title><author>Kushnir, Mark M ; Dunbar, Carmen A ; Yang, Yifei K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2023296619A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Kushnir, Mark M</creatorcontrib><creatorcontrib>Dunbar, Carmen A</creatorcontrib><creatorcontrib>Yang, Yifei K</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Kushnir, Mark M</au><au>Dunbar, Carmen A</au><au>Yang, Yifei K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for Detecting Alpha Fetoprotein Glycoforms by High Resolution Intact Mass Analysis</title><date>2023-09-21</date><risdate>2023</risdate><abstract>Methods for identifying and determining an abundance of an alpha fetoprotein (AFP) glycoform in a biological sample includes obtaining a biological sample, separating AFP from the biological sample as an enriched AFP sample, separating intact AFP from the enriched AFP sample, subjecting the intact AFP to high resolution mass spectrometry to generate a mass spectrum, identifying at least one AFP glycoform from the mass spectrum, and determining an abundance of the at least one AFP glycoform in the biological from the mass spectrum.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_US2023296619A1 |
source | esp@cenet |
subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
title | Method for Detecting Alpha Fetoprotein Glycoforms by High Resolution Intact Mass Analysis |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T15%3A38%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Kushnir,%20Mark%20M&rft.date=2023-09-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2023296619A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |