ADENO-ASSOCIATED VIRUS VARIANT CAPSIDS AND METHODS OF USE THEREOF

Provided herein are variant adeno-associated virus (AAV) capsid proteins having one or more modifications in amino acid sequence relative to a parental AAV capsid protein, which, when present in an AAV virion, confer increased infectivity of one or more types of muscle cells as compared to the infec...

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Bibliographische Detailangaben
Hauptverfasser: Kirn, David H, Schaffer, David, Kotterman, Melissa
Format: Patent
Sprache:eng
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