FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF

The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.

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Hauptverfasser: WU, Fei, ADAMS, Gregory Paul, VENKATESAN, Aranapakam M, GARDINIER, II, Thomas Courtney, MA, Kai, GERMANO, Jr., Geno J, TÜRKER, Melik Ziya, CHEN, Feng, LEE, Francis Y.F
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creator WU, Fei
ADAMS, Gregory Paul
VENKATESAN, Aranapakam M
GARDINIER, II, Thomas Courtney
MA, Kai
GERMANO, Jr., Geno J
TÜRKER, Melik Ziya
CHEN, Feng
LEE, Francis Y.F
description The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.
format Patent
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF
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