CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF

The disclosure relates to carrier particle-drug conjugates, including nanoparticle drug conjugates (NDC), that can be used in the delivery of a drug to a biological target (e.g., for targeted delivery of a cytotoxic drug to a cancer cell or tumor). Also disclosed are self-immolative linkers and link...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	WU, Fei, ADAMS, Gregory Paul, VENKATESAN, Aranapakam M, GARDINIER, II, Thomas Courtney, MA, Kai, GERMANO, JR., Geno J, TÜRKER, Melik Ziya, CHEN, Feng, LEE, Francis Y.F
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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