COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and...

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Bibliographische Detailangaben
Hauptverfasser: TIERNEY, Jason Paul, SHEPPARD, David William, HAMBLIN, Julie Nicole, BULL, Richard James, MANSOUR, Wissam, WANG, Yaode, MANDABI, Aviad, LI, Haitang, KLEPFISH, Moty, SCHMIDT, Wolfgang, ALROY, Iris, LEVANTO, Stefano
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).