TRICYCLIC COMPOUNDS AS INHIBITORS OF NLRP3

The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance...

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Hauptverfasser: VAN OPDENBOSCH, Nina, DIÉGUEZ-VÁZQUEZ, Alejandro, OEHLRICH, Daniel, LAMKANFI, Mohamed, VAN GOOL, Michiel Luc Maria, CAÑELLAS ROMAN, Santiago
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creator VAN OPDENBOSCH, Nina
DIÉGUEZ-VÁZQUEZ, Alejandro
OEHLRICH, Daniel
LAMKANFI, Mohamed
VAN GOOL, Michiel Luc Maria
CAÑELLAS ROMAN, Santiago
description The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of a disease or disorder that is associated with NLRP3 inflammasome activity.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title TRICYCLIC COMPOUNDS AS INHIBITORS OF NLRP3
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