CARBOXYESTERASE BIOCATALYSTS

The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the enginee...

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Hauptverfasser: Dorr, Brent M, Morrison, James Patrick, Fuerst, Douglas E, Brown, Kristin K, Honicker, Katherine Joyce, Plotnikov, Nikolay V, Jordan, Lydia Sanchez, Voladri, Rama, Schober, Markus
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creator Dorr, Brent M
Morrison, James Patrick
Fuerst, Douglas E
Brown, Kristin K
Honicker, Katherine Joyce
Plotnikov, Nikolay V
Jordan, Lydia Sanchez
Voladri, Rama
Schober, Markus
description The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title CARBOXYESTERASE BIOCATALYSTS
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