CD19 BINDING MOLECULES AND USES THEREOF

The present disclosure provides single domain antibodies that bind to CD19, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: PENG, Youguo, Fan, Xiaohu, ZHUANG, Qiuchuan, Zhou, Zhe, LU, Manman, Fang, Xu, HAN, Yue
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator PENG, Youguo
Fan, Xiaohu
ZHUANG, Qiuchuan
Zhou, Zhe
LU, Manman
Fang, Xu
HAN, Yue
description The present disclosure provides single domain antibodies that bind to CD19, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2023192883A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2023192883A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2023192883A13</originalsourceid><addsrcrecordid>eNrjZFB3djG0VHDy9HPx9HNX8PX3cXUO9XENVnD0c1EIDQYyQjxcg1z93XgYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXxosJGBkbGhpZGFhbGjoTFxqgBCyCRj</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>CD19 BINDING MOLECULES AND USES THEREOF</title><source>esp@cenet</source><creator>PENG, Youguo ; Fan, Xiaohu ; ZHUANG, Qiuchuan ; Zhou, Zhe ; LU, Manman ; Fang, Xu ; HAN, Yue</creator><creatorcontrib>PENG, Youguo ; Fan, Xiaohu ; ZHUANG, Qiuchuan ; Zhou, Zhe ; LU, Manman ; Fang, Xu ; HAN, Yue</creatorcontrib><description>The present disclosure provides single domain antibodies that bind to CD19, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230622&amp;DB=EPODOC&amp;CC=US&amp;NR=2023192883A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230622&amp;DB=EPODOC&amp;CC=US&amp;NR=2023192883A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PENG, Youguo</creatorcontrib><creatorcontrib>Fan, Xiaohu</creatorcontrib><creatorcontrib>ZHUANG, Qiuchuan</creatorcontrib><creatorcontrib>Zhou, Zhe</creatorcontrib><creatorcontrib>LU, Manman</creatorcontrib><creatorcontrib>Fang, Xu</creatorcontrib><creatorcontrib>HAN, Yue</creatorcontrib><title>CD19 BINDING MOLECULES AND USES THEREOF</title><description>The present disclosure provides single domain antibodies that bind to CD19, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB3djG0VHDy9HPx9HNX8PX3cXUO9XENVnD0c1EIDQYyQjxcg1z93XgYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXxosJGBkbGhpZGFhbGjoTFxqgBCyCRj</recordid><startdate>20230622</startdate><enddate>20230622</enddate><creator>PENG, Youguo</creator><creator>Fan, Xiaohu</creator><creator>ZHUANG, Qiuchuan</creator><creator>Zhou, Zhe</creator><creator>LU, Manman</creator><creator>Fang, Xu</creator><creator>HAN, Yue</creator><scope>EVB</scope></search><sort><creationdate>20230622</creationdate><title>CD19 BINDING MOLECULES AND USES THEREOF</title><author>PENG, Youguo ; Fan, Xiaohu ; ZHUANG, Qiuchuan ; Zhou, Zhe ; LU, Manman ; Fang, Xu ; HAN, Yue</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2023192883A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PENG, Youguo</creatorcontrib><creatorcontrib>Fan, Xiaohu</creatorcontrib><creatorcontrib>ZHUANG, Qiuchuan</creatorcontrib><creatorcontrib>Zhou, Zhe</creatorcontrib><creatorcontrib>LU, Manman</creatorcontrib><creatorcontrib>Fang, Xu</creatorcontrib><creatorcontrib>HAN, Yue</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PENG, Youguo</au><au>Fan, Xiaohu</au><au>ZHUANG, Qiuchuan</au><au>Zhou, Zhe</au><au>LU, Manman</au><au>Fang, Xu</au><au>HAN, Yue</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CD19 BINDING MOLECULES AND USES THEREOF</title><date>2023-06-22</date><risdate>2023</risdate><abstract>The present disclosure provides single domain antibodies that bind to CD19, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2023192883A1
source esp@cenet
subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title CD19 BINDING MOLECULES AND USES THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T10%3A40%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PENG,%20Youguo&rft.date=2023-06-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2023192883A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true