PD-L1 variants with improved affinity towards PD-1

The present invention relates to a PD-L1 polypeptide comprising at least a first amino acid sequence at least 70% identical to SEQ ID NO:8, and at least a second sequence at least 70% identical to SEQ ID NO: 10, wherein the polypeptide carries amino acid substitutions at least at the amino acid posi...

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Hauptverfasser:	WIECHMANN, Svenja, PUTYRSKI, Mateusz, PARNHAM, Michael John, ERNST, Andreas, VON KNETHEN, Andreas
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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