NOVEL CERIUM OXIDE NANOCOMPLEX AND A COMPOSITION FOR PREVENTING OR TREATING LIVER FAILURE COMPRISING THE SAME

A cerium oxide nanocomplex, a composition containing the cerium oxide nanocomplex as an active ingredient, and their uses for preventing or treating inflammatory liver disease are disclosed. The present disclosure applies a biocompatible polymer composed of an optimal combination to significantly im...

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Bibliographische Detailangaben
Hauptverfasser: Jeon, So-Hyun, KI, Seul Ki
Format: Patent
Sprache:eng
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Zusammenfassung:A cerium oxide nanocomplex, a composition containing the cerium oxide nanocomplex as an active ingredient, and their uses for preventing or treating inflammatory liver disease are disclosed. The present disclosure applies a biocompatible polymer composed of an optimal combination to significantly improve the biomedical stability, biosynthesis and efficiency of the production process of nanoparticles while maintaining the nanoparticles' excellent inhibitory activity against inflammation. In particular, the present disclosure may be applied as an effective therapeutic composition that effectively controls excessive immune response and inflammatory response and tissue injury in acute liver failure which is a serious condition of rapid loss of liver function that results in multiple organ failure and death.