COMPOSITIONS AND METHODS FOR GENERATING SYNTHETIC LETHALITY IN TUMORS

The present disclosure provides methods for treating cancer comprising administering one or more therapeutic agents for manipulation of a target gene (e.g., protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1)), wherein the cancer has a mutation in, an altered (e.g., increased or decrea...

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Bibliographische Detailangaben
Hauptverfasser: TURPAZ, Yaron, BREW, Christine Taylor, XIAO, Yuanyuan, HARRISON, Stephen David, WINTHER, Michael David, YOST, Shawn
Format: Patent
Sprache:eng
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