QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS

QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS

The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic u...

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Hauptverfasser: BEATO, Claudia, GIULIANI, Marta, ARMANI, Elisabetta, AMARI, Gabriele, PAGANO, Mafalda, RAVEGLIA, Luca
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator BEATO, Claudia
GIULIANI, Marta
ARMANI, Elisabetta
AMARI, Gabriele
PAGANO, Mafalda
RAVEGLIA, Luca
description The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
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