FLUORESCENT DYE IN TERNARY COMPLEX

FLUORESCENT DYE IN TERNARY COMPLEX

Pharmaceutical compositions and methods are presented for creating a ternary structure involving a fluorescent molecule, an intermediate carrier molecule, and a larger protein or polymer with a binding site receptive to the intermediate molecule or fluorescent/intermediate complex. The resulting ter...

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Hauptverfasser: Zimmer, Robin D, Cable, Adam Michael, Feldschuh, Jonathan, Muller, Boyce Lee, Anzellotti, Atilio, Jordan, Nancy Tommye
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Zimmer, Robin D
Cable, Adam Michael
Feldschuh, Jonathan
Muller, Boyce Lee
Anzellotti, Atilio
Jordan, Nancy Tommye
description Pharmaceutical compositions and methods are presented for creating a ternary structure involving a fluorescent molecule, an intermediate carrier molecule, and a larger protein or polymer with a binding site receptive to the intermediate molecule or fluorescent/intermediate complex. The resulting ternary system improves the binding stability of the fluorescent dye to the protein, both in-vivo and in-vitro. This improved stability results in a longer half-life in medical use, enabling improved qualitative and quantitative use of the dye.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title FLUORESCENT DYE IN TERNARY COMPLEX
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