LIQUID COMPOSITION COMPRISING IBUPROFEN AND PHENYLEPHRINE

The present invention relates to a liquid pharmaceutical composition for oral administration in the form of suspension which comprises the combination of ibuprofen and phenylephrine, or a pharmaceutically acceptable salt thereof, as active substances, and hypromellose, xanthan gum, liquid maltitol,...

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Hauptverfasser: SÁNCHEZ GARCÍA, José Ángel, SANTE SERNA, Luis, SANZ MENÉNDEZ, Nuria, VICARIO DE LA TORRE, Marta, IGLESIAS SÁNCHEZ, José Carlos
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creator SÁNCHEZ GARCÍA, José Ángel
SANTE SERNA, Luis
SANZ MENÉNDEZ, Nuria
VICARIO DE LA TORRE, Marta
IGLESIAS SÁNCHEZ, José Carlos
description The present invention relates to a liquid pharmaceutical composition for oral administration in the form of suspension which comprises the combination of ibuprofen and phenylephrine, or a pharmaceutically acceptable salt thereof, as active substances, and hypromellose, xanthan gum, liquid maltitol, glycerine and water. The composition is stable, has good organoleptical properties and shows excellent pharmacokinetic profile, providing quick absorption of the drugs. The present invention also relates to the use of the composition for treating the symptoms of flu and common cold, particularly in adults and in children over 7 years.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title LIQUID COMPOSITION COMPRISING IBUPROFEN AND PHENYLEPHRINE
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