SMALL CATIONIC ORTHO-5,15-DI-HETEROARYL-PORPHYRINS DERIVATIVES AND THEIR APPLICATIONS IN PHOTOINACTIVATION OF MICROORGANISMS
The present invention relates to small cationic ortho-5,15-di-heteroaryl porphyrin derivatives, in particular porphyrins, chlorins or bacteriochlorin of formula (I) or pharmaceutically acceptable salts thereof.This invention also relates to the use of the above-mentioned cationic ortho-5,10-di-heter...
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| creator | SALVADOR BAGNATO, Vanderiei DA SILVA ARNAUT MOREIRA, Luis Guilerne DOS SANTOS VINAGREIRO, Carolina MIGUÉNS PEREIRA, Maria MAYUMI INADA, Natalia DUARTE JORGE DA SILVA, Gabriela conceiçåo BLANCO, Kate Cristina |
| description | The present invention relates to small cationic ortho-5,15-di-heteroaryl porphyrin derivatives, in particular porphyrins, chlorins or bacteriochlorin of formula (I) or pharmaceutically acceptable salts thereof.This invention also relates to the use of the above-mentioned cationic ortho-5,10-di-heteroaryl porphyrin derivatives of Formula (I) or a pharmaceutically acceptable salts thereof, in photodynamic inactivation of microorganisms, where the referred derivatives are able to treat the same in the presence of an adequate light.The present invention also describes pharmaceutical compositions comprising one or more of the cationic ortho-5,10-di-heteroaryl porphyrin derivatives, in particular prophyrins, chlorins or bacteriochlorins of Formula (I), or pharmaceutically acceptable salts thereof, for the treatment of bacterial and/or fungi and/or yeasts and/or viral infections, in humans or animals. |
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HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221124&DB=EPODOC&CC=US&NR=2022372043A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221124&DB=EPODOC&CC=US&NR=2022372043A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SALVADOR BAGNATO, Vanderiei</creatorcontrib><creatorcontrib>DA SILVA ARNAUT MOREIRA, Luis Guilerne</creatorcontrib><creatorcontrib>DOS SANTOS VINAGREIRO, Carolina</creatorcontrib><creatorcontrib>MIGUÉNS PEREIRA, Maria</creatorcontrib><creatorcontrib>MAYUMI INADA, Natalia</creatorcontrib><creatorcontrib>DUARTE JORGE DA SILVA, Gabriela conceiçåo</creatorcontrib><creatorcontrib>BLANCO, Kate Cristina</creatorcontrib><title>SMALL CATIONIC ORTHO-5,15-DI-HETEROARYL-PORPHYRINS DERIVATIVES AND THEIR APPLICATIONS IN PHOTOINACTIVATION OF MICROORGANISMS</title><description>The present invention relates to small cationic ortho-5,15-di-heteroaryl porphyrin derivatives, in particular porphyrins, chlorins or bacteriochlorin of formula (I) or pharmaceutically acceptable salts thereof.This invention also relates to the use of the above-mentioned cationic ortho-5,10-di-heteroaryl porphyrin derivatives of Formula (I) or a pharmaceutically acceptable salts thereof, in photodynamic inactivation of microorganisms, where the referred derivatives are able to treat the same in the presence of an adequate light.The present invention also describes pharmaceutical compositions comprising one or more of the cationic ortho-5,10-di-heteroaryl porphyrin derivatives, in particular prophyrins, chlorins or bacteriochlorins of Formula (I), or pharmaceutically acceptable salts thereof, for the treatment of bacterial and/or fungi and/or yeasts and/or viral infections, in humans or animals.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLsKwjAUQLs4iPoPF1wN9GFxDmlqLrS54SYWOpUicRIt1NGPV9QPcDrLOWeZPH0rmwaUDEgWFRAHQ6LcZaWoUBgdNJPkvhGO2Jme0XqoNGP3DjrtQdoKgtHIIJ1r8PvxgBacoUBopQofmSxQDS0qJuKjtOhbv04Wl_E6x82Pq2Rb66CMiNN9iPM0nuMtPoaTz9M8Lw55ui9kVvxnvQCnPzyF</recordid><startdate>20221124</startdate><enddate>20221124</enddate><creator>SALVADOR BAGNATO, Vanderiei</creator><creator>DA SILVA ARNAUT MOREIRA, Luis Guilerne</creator><creator>DOS SANTOS VINAGREIRO, Carolina</creator><creator>MIGUÉNS PEREIRA, Maria</creator><creator>MAYUMI INADA, Natalia</creator><creator>DUARTE JORGE DA SILVA, Gabriela conceiçåo</creator><creator>BLANCO, Kate Cristina</creator><scope>EVB</scope></search><sort><creationdate>20221124</creationdate><title>SMALL CATIONIC ORTHO-5,15-DI-HETEROARYL-PORPHYRINS DERIVATIVES AND THEIR APPLICATIONS IN PHOTOINACTIVATION OF MICROORGANISMS</title><author>SALVADOR BAGNATO, Vanderiei ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SMALL CATIONIC ORTHO-5,15-DI-HETEROARYL-PORPHYRINS DERIVATIVES AND THEIR APPLICATIONS IN PHOTOINACTIVATION OF MICROORGANISMS |
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