Monoacylglycerol Lipase Modulators

Bridged compounds of Formula (I) and Formula (II), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric d...

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Hauptverfasser: Chen, Gang, Laforteza, Brian Ngo, Huang, Chaofeng, Ravula, Suchitra, Ameriks, Michael K, Zhang, Wei
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creator Chen, Gang
Laforteza, Brian Ngo
Huang, Chaofeng
Ravula, Suchitra
Ameriks, Michael K
Zhang, Wei
description Bridged compounds of Formula (I) and Formula (II), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, bipolar disorder), cancers and eye conditions.wherein R2, R3 R4, R5 and R6 are defined herein.
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Monoacylglycerol Lipase Modulators
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