Methods of Purifying Masked Antibodies

The present invention relates to the field of antibody formulations. In particular, the present invention relates to specific methods of preparing masked antibodies with reduced aggregation. In some embodiments, the masked antibodies comprise anti-CD47 antibodies.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Leiske, Danielle, Eakin, Catherine, Westendorf, Lori, Cunningham, Elise, Lee, Susan, Beam, Kevin, Alcoba, Samuel Pearce, Feldhaus, Michael
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Leiske, Danielle
Eakin, Catherine
Westendorf, Lori
Cunningham, Elise
Lee, Susan
Beam, Kevin
Alcoba, Samuel Pearce
Feldhaus, Michael
description The present invention relates to the field of antibody formulations. In particular, the present invention relates to specific methods of preparing masked antibodies with reduced aggregation. In some embodiments, the masked antibodies comprise anti-CD47 antibodies.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2022306727A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2022306727A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2022306727A13</originalsourceid><addsrcrecordid>eNrjZFDzTS3JyE8pVshPUwgoLcpMq8zMS1fwTSzOTk1RcMwryUzKT8lMLeZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGRkbGBmbmRuaOhsbEqQIA8VQoPA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Methods of Purifying Masked Antibodies</title><source>esp@cenet</source><creator>Leiske, Danielle ; Eakin, Catherine ; Westendorf, Lori ; Cunningham, Elise ; Lee, Susan ; Beam, Kevin ; Alcoba, Samuel Pearce ; Feldhaus, Michael</creator><creatorcontrib>Leiske, Danielle ; Eakin, Catherine ; Westendorf, Lori ; Cunningham, Elise ; Lee, Susan ; Beam, Kevin ; Alcoba, Samuel Pearce ; Feldhaus, Michael</creatorcontrib><description>The present invention relates to the field of antibody formulations. In particular, the present invention relates to specific methods of preparing masked antibodies with reduced aggregation. In some embodiments, the masked antibodies comprise anti-CD47 antibodies.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220929&amp;DB=EPODOC&amp;CC=US&amp;NR=2022306727A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220929&amp;DB=EPODOC&amp;CC=US&amp;NR=2022306727A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Leiske, Danielle</creatorcontrib><creatorcontrib>Eakin, Catherine</creatorcontrib><creatorcontrib>Westendorf, Lori</creatorcontrib><creatorcontrib>Cunningham, Elise</creatorcontrib><creatorcontrib>Lee, Susan</creatorcontrib><creatorcontrib>Beam, Kevin</creatorcontrib><creatorcontrib>Alcoba, Samuel Pearce</creatorcontrib><creatorcontrib>Feldhaus, Michael</creatorcontrib><title>Methods of Purifying Masked Antibodies</title><description>The present invention relates to the field of antibody formulations. In particular, the present invention relates to specific methods of preparing masked antibodies with reduced aggregation. In some embodiments, the masked antibodies comprise anti-CD47 antibodies.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFDzTS3JyE8pVshPUwgoLcpMq8zMS1fwTSzOTk1RcMwryUzKT8lMLeZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfGhwUYGRkbGBmbmRuaOhsbEqQIA8VQoPA</recordid><startdate>20220929</startdate><enddate>20220929</enddate><creator>Leiske, Danielle</creator><creator>Eakin, Catherine</creator><creator>Westendorf, Lori</creator><creator>Cunningham, Elise</creator><creator>Lee, Susan</creator><creator>Beam, Kevin</creator><creator>Alcoba, Samuel Pearce</creator><creator>Feldhaus, Michael</creator><scope>EVB</scope></search><sort><creationdate>20220929</creationdate><title>Methods of Purifying Masked Antibodies</title><author>Leiske, Danielle ; Eakin, Catherine ; Westendorf, Lori ; Cunningham, Elise ; Lee, Susan ; Beam, Kevin ; Alcoba, Samuel Pearce ; Feldhaus, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2022306727A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Leiske, Danielle</creatorcontrib><creatorcontrib>Eakin, Catherine</creatorcontrib><creatorcontrib>Westendorf, Lori</creatorcontrib><creatorcontrib>Cunningham, Elise</creatorcontrib><creatorcontrib>Lee, Susan</creatorcontrib><creatorcontrib>Beam, Kevin</creatorcontrib><creatorcontrib>Alcoba, Samuel Pearce</creatorcontrib><creatorcontrib>Feldhaus, Michael</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Leiske, Danielle</au><au>Eakin, Catherine</au><au>Westendorf, Lori</au><au>Cunningham, Elise</au><au>Lee, Susan</au><au>Beam, Kevin</au><au>Alcoba, Samuel Pearce</au><au>Feldhaus, Michael</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Methods of Purifying Masked Antibodies</title><date>2022-09-29</date><risdate>2022</risdate><abstract>The present invention relates to the field of antibody formulations. In particular, the present invention relates to specific methods of preparing masked antibodies with reduced aggregation. In some embodiments, the masked antibodies comprise anti-CD47 antibodies.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2022306727A1
source esp@cenet
subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Methods of Purifying Masked Antibodies
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T23%3A04%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Leiske,%20Danielle&rft.date=2022-09-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2022306727A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true