Genome Engineering

Methods are provided for altering target DNA in a cell genetically modified to express a Cas 9 enzyme that forms a co-localization complex with a guide RNA complementary to the target DNA and that cleaves the target DNA in a site specific manner Methods include introducing into the cell a first fore...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Joyce Lichi, Church, George M, Yang, Luhan, Guell, Marc
Format: Patent
Sprache:eng
Schlagworte:
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