NEAR-INFRARED (NIR) QUALITY MONITORING METHOD USED IN COLUMN CHROMATOGRAPHY FOR EXTRACTING CONJUGATED ESTROGENS (CEs) FROM PREGNANT MARE URINE (PMU)
A near-infrared (NIR) quality monitoring method used in column chromatography for extracting conjugated estrogens (CEs) from pregnant mare urine (PMU), that includes steps of: collecting an eluate obtained from column chromatography of a PMU stock solution as a to-be-tested sample; subjecting the to...
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| creator | Xu, Zhiyong Guo, Tuo Ma, Jinfang Huang, Qunqun Chang, Zhanying Xiao, Xue Zeng, Jiangbo Luo, Jun Gao, Xiaoli |
| description | A near-infrared (NIR) quality monitoring method used in column chromatography for extracting conjugated estrogens (CEs) from pregnant mare urine (PMU), that includes steps of: collecting an eluate obtained from column chromatography of a PMU stock solution as a to-be-tested sample; subjecting the to-be-tested sample to near-infrared spectroscopy (NIRS) to obtain raw spectral data, eliminating abnormal spectral values from the raw spectral data by a Mahalanobis distance method based on L1-PCA, and importing spectral data obtained after the abnormal spectral values are eliminated into a correction model to obtain a CE content in the to-be-tested sample; the correction model is a linear equation illustrating a relationship between true values and measured values, and the measured values refer to the NIR spectral data obtained after the abnormal spectral values are eliminated; and the CEs comprise one or more of sodium 17α-dihydroequilin sulfate, sodium equilin sulfate, and sodium estrone sulfate. |
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subjecting the to-be-tested sample to near-infrared spectroscopy (NIRS) to obtain raw spectral data, eliminating abnormal spectral values from the raw spectral data by a Mahalanobis distance method based on L1-PCA, and importing spectral data obtained after the abnormal spectral values are eliminated into a correction model to obtain a CE content in the to-be-tested sample; the correction model is a linear equation illustrating a relationship between true values and measured values, and the measured values refer to the NIR spectral data obtained after the abnormal spectral values are eliminated; and the CEs comprise one or more of sodium 17α-dihydroequilin sulfate, sodium equilin sulfate, and sodium estrone sulfate.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
| title | NEAR-INFRARED (NIR) QUALITY MONITORING METHOD USED IN COLUMN CHROMATOGRAPHY FOR EXTRACTING CONJUGATED ESTROGENS (CEs) FROM PREGNANT MARE URINE (PMU) |
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