USE OF LOW PH AND DEXTRAN SULFATE DURING HARVEST TREATMENT FOR PROTEIN PURIFICATION

USE OF LOW PH AND DEXTRAN SULFATE DURING HARVEST TREATMENT FOR PROTEIN PURIFICATION

In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, comprising: (a) contacting the mixture with a dextran polymer under conditions suitable for the dextran polymer to bind to o...

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Hauptverfasser: Tan, Zhijun, Li, Zhengjian, Huang, Chao, Jin, Mi, Martel, JR., Richard P, Singh, Nripen, Lewandowski, Angela T
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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creator Tan, Zhijun
Li, Zhengjian
Huang, Chao
Jin, Mi
Martel, JR., Richard P
Singh, Nripen
Lewandowski, Angela T
description In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, comprising: (a) contacting the mixture with a dextran polymer under conditions suitable for the dextran polymer to bind to one or more contaminants, thereby to form a contaminant precipitate; (b) separating the contaminant precipitate from the mixture to form a solution, thereby purifying the protein of interest.
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Lewandowski, Angela T</creatorcontrib><description>In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, comprising: (a) contacting the mixture with a dextran polymer under conditions suitable for the dextran polymer to bind to one or more contaminants, thereby to form a contaminant precipitate; (b) separating the contaminant precipitate from the mixture to form a solution, thereby purifying the protein of interest.</description><language>eng</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220526&amp;DB=EPODOC&amp;CC=US&amp;NR=2022162260A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220526&amp;DB=EPODOC&amp;CC=US&amp;NR=2022162260A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Tan, Zhijun</creatorcontrib><creatorcontrib>Li, Zhengjian</creatorcontrib><creatorcontrib>Huang, Chao</creatorcontrib><creatorcontrib>Jin, Mi</creatorcontrib><creatorcontrib>Martel, JR., Richard P</creatorcontrib><creatorcontrib>Singh, Nripen</creatorcontrib><creatorcontrib>Lewandowski, Angela T</creatorcontrib><title>USE OF LOW PH AND DEXTRAN SULFATE DURING HARVEST TREATMENT FOR PROTEIN PURIFICATION</title><description>In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, comprising: (a) contacting the mixture with a dextran polymer under conditions suitable for the dextran polymer to bind to one or more contaminants, thereby to form a contaminant precipitate; 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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title USE OF LOW PH AND DEXTRAN SULFATE DURING HARVEST TREATMENT FOR PROTEIN PURIFICATION
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