DIFFERENTIATION METHOD OF NEURAL STEM CELLS MANUFACTURED BY DIRECT CELL CONVERSION INTO ASTROCYTES
The present invention relates to a method for efficiently differentiating neural stem cells into astrocytes and, more particularly, to a cell conversion-based method for more efficiently differentiating human neural stem cells into astrocytes that exhibit immune response suppression ability within a...
Gespeichert in:
Hauptverfasser: | , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | HONG, Sung Hoi JANG, Ahyoung CHOI, Kyung-Ah |
description | The present invention relates to a method for efficiently differentiating neural stem cells into astrocytes and, more particularly, to a cell conversion-based method for more efficiently differentiating human neural stem cells into astrocytes that exhibit immune response suppression ability within a short period of time. Unlike a conventional method, the method for differentiating neural stem cells into astrocytes by using a differentiation medium containing a combination of several cytokines, according to the present invention, involves a shortened differentiation time and has excellent differentiation efficiency, and the differentiated astrocytes exhibit immune response suppression ability, and thus can be useful as an agent for treating various brain diseases such as degenerative neurological diseases. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2022119765A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2022119765A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2022119765A13</originalsourceid><addsrcrecordid>eNqNjDsKAjEUANNYiHqHB9aCiehiGZMXNpAPJC_CVssqsRJdWO-PKB7AaooZZs4u2hqDCQNZSTYG8Eht1BANBCxJOsiEHhQ6l8HLUIxUVBJqOHWgbUJFXwkqhjOm_FnYQBFkphRVR5iXbHYb7lNd_bhga4Ok2k0dn32dxuFaH_XVlyy2QnB-bA57yXf_VW_Q8jUt</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>DIFFERENTIATION METHOD OF NEURAL STEM CELLS MANUFACTURED BY DIRECT CELL CONVERSION INTO ASTROCYTES</title><source>esp@cenet</source><creator>HONG, Sung Hoi ; JANG, Ahyoung ; CHOI, Kyung-Ah</creator><creatorcontrib>HONG, Sung Hoi ; JANG, Ahyoung ; CHOI, Kyung-Ah</creatorcontrib><description>The present invention relates to a method for efficiently differentiating neural stem cells into astrocytes and, more particularly, to a cell conversion-based method for more efficiently differentiating human neural stem cells into astrocytes that exhibit immune response suppression ability within a short period of time. Unlike a conventional method, the method for differentiating neural stem cells into astrocytes by using a differentiation medium containing a combination of several cytokines, according to the present invention, involves a shortened differentiation time and has excellent differentiation efficiency, and the differentiated astrocytes exhibit immune response suppression ability, and thus can be useful as an agent for treating various brain diseases such as degenerative neurological diseases.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220421&DB=EPODOC&CC=US&NR=2022119765A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220421&DB=EPODOC&CC=US&NR=2022119765A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HONG, Sung Hoi</creatorcontrib><creatorcontrib>JANG, Ahyoung</creatorcontrib><creatorcontrib>CHOI, Kyung-Ah</creatorcontrib><title>DIFFERENTIATION METHOD OF NEURAL STEM CELLS MANUFACTURED BY DIRECT CELL CONVERSION INTO ASTROCYTES</title><description>The present invention relates to a method for efficiently differentiating neural stem cells into astrocytes and, more particularly, to a cell conversion-based method for more efficiently differentiating human neural stem cells into astrocytes that exhibit immune response suppression ability within a short period of time. Unlike a conventional method, the method for differentiating neural stem cells into astrocytes by using a differentiation medium containing a combination of several cytokines, according to the present invention, involves a shortened differentiation time and has excellent differentiation efficiency, and the differentiated astrocytes exhibit immune response suppression ability, and thus can be useful as an agent for treating various brain diseases such as degenerative neurological diseases.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDsKAjEUANNYiHqHB9aCiehiGZMXNpAPJC_CVssqsRJdWO-PKB7AaooZZs4u2hqDCQNZSTYG8Eht1BANBCxJOsiEHhQ6l8HLUIxUVBJqOHWgbUJFXwkqhjOm_FnYQBFkphRVR5iXbHYb7lNd_bhga4Ok2k0dn32dxuFaH_XVlyy2QnB-bA57yXf_VW_Q8jUt</recordid><startdate>20220421</startdate><enddate>20220421</enddate><creator>HONG, Sung Hoi</creator><creator>JANG, Ahyoung</creator><creator>CHOI, Kyung-Ah</creator><scope>EVB</scope></search><sort><creationdate>20220421</creationdate><title>DIFFERENTIATION METHOD OF NEURAL STEM CELLS MANUFACTURED BY DIRECT CELL CONVERSION INTO ASTROCYTES</title><author>HONG, Sung Hoi ; JANG, Ahyoung ; CHOI, Kyung-Ah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2022119765A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>HONG, Sung Hoi</creatorcontrib><creatorcontrib>JANG, Ahyoung</creatorcontrib><creatorcontrib>CHOI, Kyung-Ah</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HONG, Sung Hoi</au><au>JANG, Ahyoung</au><au>CHOI, Kyung-Ah</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIFFERENTIATION METHOD OF NEURAL STEM CELLS MANUFACTURED BY DIRECT CELL CONVERSION INTO ASTROCYTES</title><date>2022-04-21</date><risdate>2022</risdate><abstract>The present invention relates to a method for efficiently differentiating neural stem cells into astrocytes and, more particularly, to a cell conversion-based method for more efficiently differentiating human neural stem cells into astrocytes that exhibit immune response suppression ability within a short period of time. Unlike a conventional method, the method for differentiating neural stem cells into astrocytes by using a differentiation medium containing a combination of several cytokines, according to the present invention, involves a shortened differentiation time and has excellent differentiation efficiency, and the differentiated astrocytes exhibit immune response suppression ability, and thus can be useful as an agent for treating various brain diseases such as degenerative neurological diseases.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_US2022119765A1 |
source | esp@cenet |
subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
title | DIFFERENTIATION METHOD OF NEURAL STEM CELLS MANUFACTURED BY DIRECT CELL CONVERSION INTO ASTROCYTES |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T23%3A25%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HONG,%20Sung%20Hoi&rft.date=2022-04-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2022119765A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |