PEPTIDE AND METHOD FOR MANUFACTURING SAME

PEPTIDE AND METHOD FOR MANUFACTURING SAME

A peptide having a fluoroalkyl group as its side chain and a method for producing, which comprises condensing a compound represented by the formula (6-2) or (6-4), where means that an asymmetric carbon atom has an absolute configuration of S or R, Rf is a C1-30 alkyl group which is substituted with...

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Hauptverfasser: MORIMOTO, Jumpei, SANDO, Shinsuke, ONO, Takahiro, OKAZOE, Takashi, ISHIBASHI, Yuichiro, AIKAWA, Kohsuke, MIKAMI, Toshiki
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Sprache:eng
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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creator MORIMOTO, Jumpei
SANDO, Shinsuke
ONO, Takahiro
OKAZOE, Takashi
ISHIBASHI, Yuichiro
AIKAWA, Kohsuke
MIKAMI, Toshiki
description A peptide having a fluoroalkyl group as its side chain and a method for producing, which comprises condensing a compound represented by the formula (6-2) or (6-4), where means that an asymmetric carbon atom has an absolute configuration of S or R, Rf is a C1-30 alkyl group which is substituted with at least two fluorine atoms, and which may further be substituted with a halogen atom other than a fluorine atom (when the C1-30 alkyl group is a C2-30 alkyl group, it may have 1 to 5 etheric oxygen atoms between carbon atoms), and R2 is a protecting group for the amino group, with a fluorinated amino acid having its carboxy group protected, an amino acid having its carboxy group protected, a fluorinated peptide having its C-terminal protected, or a peptide having its C-terminal protected.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title PEPTIDE AND METHOD FOR MANUFACTURING SAME
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