ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF

ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF

Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sharma, Manoj, Smirnov, Yuriy, Draghici, Bogdan, Teng, Zhu, Dominowski, Allison, Yau, Heungyeung, Morjana, Nihmat, Zheng, Yi Feng, Bedzyk, William, Lebedeva, Tatiana, Mareeva, Tatiana
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disclosed are methods of reducing naloxone or naltrexone interference in opiate assays using the antibodies.