IMPLANTABLE DEVICES FOR CELL THERAPY AND RELATED METHODS

Described herein are implantable devices comprising means for mitigating the foreign body response (FBR) and at least one cell-containing compartment which comprises a plurality of cells (e.g., live cells) encapsulated in a polymer composition comprising a cell-binding substance (CBS), as well as co...

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Hauptverfasser: Miller, Robert James, Heidebrecht, Richard, Yin, Zoe, Peritt, David, Carmona, Guillaume, Johnston, Erika Ellen, Oberli, Matthias Alexander, Wotton, Paul Kevin, Veiseh, Omid, Barney, Lauren Emily, Beauregard, Michael, Smith, Devyn McKinley, Gonzalez, Francisco Caballero, O'Connor, Owen, Sewell, Jared A
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creator Miller, Robert James
Heidebrecht, Richard
Yin, Zoe
Peritt, David
Carmona, Guillaume
Johnston, Erika Ellen
Oberli, Matthias Alexander
Wotton, Paul Kevin
Veiseh, Omid
Barney, Lauren Emily
Beauregard, Michael
Smith, Devyn McKinley
Gonzalez, Francisco Caballero
O'Connor, Owen
Sewell, Jared A
description Described herein are implantable devices comprising means for mitigating the foreign body response (FBR) and at least one cell-containing compartment which comprises a plurality of cells (e.g., live cells) encapsulated in a polymer composition comprising a cell-binding substance (CBS), as well as compositions and methods of making and using the same. The cells are capable of expressing a therapeutic agent useful for the treatment of a disease, disorder, or condition described herein.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title IMPLANTABLE DEVICES FOR CELL THERAPY AND RELATED METHODS
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