INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE
The hemitartrate salt of a compound represented by the following structural formula:(Formula 1 Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical...
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| creator | PETERSCHMITT, Judith SIEGEL, Craig WILLIS, Chris MARSHALL, John HARIANAWALA, Abizer LIU, Hanlan CHENG, Seng COPELAND, Diane P BHARDWAJ, Renu SKELL, Jeffrey PALACE, Gerard KOCHLING, Jianmei |
| description | The hemitartrate salt of a compound represented by the following structural formula:(Formula 1 Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described. |
| format | Patent |
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Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE |
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