HUMANIZED ANTI-SIRP ALPHA ANTIBODIES

The present invention relates to humanized antibodies against SIRPα that are suitable for use in anti-cancer therapy. The invention further relates to the use of the humanized anti-SIRPα antibodies in the treatment of human solid tumours and haematological malignancies, optionally in combination wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: VERHEIJDEN, Gijsbertus Franciscus Maria
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to humanized antibodies against SIRPα that are suitable for use in anti-cancer therapy. The invention further relates to the use of the humanized anti-SIRPα antibodies in the treatment of human solid tumours and haematological malignancies, optionally in combination with further anti-cancer therapeutics.