ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS

Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resista...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Boock, Robert J, Dring, Chris W
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Devices are provided for measurement of an analyte concentration, e.g., glucose in a host. The device can include a sensor configured to generate a signal associated with a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises a diffusion resistance domain configured to control a flux of the analyte therethrough. The diffusion resistance domain comprises one or more zwitterionic compounds and a base polymer comprising both hydrophilic and hydrophobic regions.