Disubstituted Octahydropyrrolo[3,4-c]Pyrroles As Orexin Receptor Modulators

Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.

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Hauptverfasser: Sappey, Kathleen C, Shireman, Brock T, Chai, Wenying, Shah, Chandravadan R, Letavic, Michael A, Rudolph, Dale A, Stocking, Emily M, Ly, Kiev S, Johnson, Akinola Soyode, Pippel, Daniel J, Savall, Brad M, Swanson, Devin M
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creator Sappey, Kathleen C
Shireman, Brock T
Chai, Wenying
Shah, Chandravadan R
Letavic, Michael A
Rudolph, Dale A
Stocking, Emily M
Ly, Kiev S
Johnson, Akinola Soyode
Pippel, Daniel J
Savall, Brad M
Swanson, Devin M
description Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Disubstituted Octahydropyrrolo[3,4-c]Pyrroles As Orexin Receptor Modulators
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