Disubstituted Octahydropyrrolo[3,4-c]Pyrroles As Orexin Receptor Modulators
Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.
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creator | Sappey, Kathleen C Shireman, Brock T Chai, Wenying Shah, Chandravadan R Letavic, Michael A Rudolph, Dale A Stocking, Emily M Ly, Kiev S Johnson, Akinola Soyode Pippel, Daniel J Savall, Brad M Swanson, Devin M |
description | Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | Disubstituted Octahydropyrrolo[3,4-c]Pyrroles As Orexin Receptor Modulators |
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