PHARMACEUTICAL SALTS OF PYRIMIDINE DERIVATIVES AND METHOD OF TREATING DISORDERS

The present disclosure relates to pharmaceutical salts and polymorphic forms of forms of pyrimidine derivatives that have inhibitory activities against mutant epidermal growth factor receptor (EGFR). The present disclosure further relates to the processes for the preparation of the pyrimidine deriva...

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Hauptverfasser: Sharma, Pradeep Kumar, Langston, Marianne, DURAK, Landon J, Li, Shuanglian, Nguyen, Thai Hiep, Zhang, Xiaoguang
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creator Sharma, Pradeep Kumar
Langston, Marianne
DURAK, Landon J
Li, Shuanglian
Nguyen, Thai Hiep
Zhang, Xiaoguang
description The present disclosure relates to pharmaceutical salts and polymorphic forms of forms of pyrimidine derivatives that have inhibitory activities against mutant epidermal growth factor receptor (EGFR). The present disclosure further relates to the processes for the preparation of the pyrimidine derivatives and to the pharmaceutical salts and the polymorphic forms of the pyrimidine derivatives.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHARMACEUTICAL SALTS OF PYRIMIDINE DERIVATIVES AND METHOD OF TREATING DISORDERS
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