AAV VARIANTS WITH ENHANCED TROPISM

The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.

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Hauptverfasser: Sah, Dinah Wen-Yee, Huang, Qin, Ren, Xiao-Qin, Carroll Soper, Jenna, Adachi, Kei, Deverman, Benjamin E, Hou, Jinzhao, Chen, Qingmin, Wang, Wei, Ren, Amy, Gradinaru, Viviana
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creator Sah, Dinah Wen-Yee
Huang, Qin
Ren, Xiao-Qin
Carroll Soper, Jenna
Adachi, Kei
Deverman, Benjamin E
Hou, Jinzhao
Chen, Qingmin
Wang, Wei
Ren, Amy
Gradinaru, Viviana
description The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.
format Patent
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title AAV VARIANTS WITH ENHANCED TROPISM
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