AGENTS, USES AND METHODS FOR THE TREATMENT OF SYNUCLEINOPATHY

The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheim...

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Hauptverfasser: VINK, Tom, VESTERAGER, Louise Buur, MONTEZINHO, Liliana Christina Pereira, FOG, Karina, SATIJN, David, KALLUNKI, Pekka, BERGSTRÔM, Ann-Louise, RADEMAKER, Rik, MALIK, Ibrahim John, VAN DEN BRINK, Edward, SOTTY, Florence, PARREN, Paul
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creator VINK, Tom
VESTERAGER, Louise Buur
MONTEZINHO, Liliana Christina Pereira
FOG, Karina
SATIJN, David
KALLUNKI, Pekka
BERGSTRÔM, Ann-Louise
RADEMAKER, Rik
MALIK, Ibrahim John
VAN DEN BRINK, Edward
SOTTY, Florence
PARREN, Paul
description The invention relates to novel monoclonal anti-alpha-synuclein antibodies. The antibodies can be used for treating a synucleinopathy such as Parkinson's disease (including idiopathic and inherited forms of Parkinson's disease), Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title AGENTS, USES AND METHODS FOR THE TREATMENT OF SYNUCLEINOPATHY
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