CARBOXYESTERASE BIOCATALYSTS

The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the enginee...

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Hauptverfasser: HONICKER, Katherina Joyce, BROWN, Kristin K, MORRISON, James Patrick, PLOTNIKOV, Nikolay V, JORDAN, Lydia Sanchez, DORR, Brent M, SCHOBER, Markus, VOLADRI, Rama, FUERST, Douglas E
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creator HONICKER, Katherina Joyce
BROWN, Kristin K
MORRISON, James Patrick
PLOTNIKOV, Nikolay V
JORDAN, Lydia Sanchez
DORR, Brent M
SCHOBER, Markus
VOLADRI, Rama
FUERST, Douglas E
description The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title CARBOXYESTERASE BIOCATALYSTS
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