METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS
In step A), ≥30 to ≤40 mol of acetic acid, ≥0.3 to ≤1 mol of sulfuric acid and ≥0.9 to ≤2.5 mol of water are used per mole of compounds of the formula (II). The method is particularly suitable for the synthesis of the intermediate (I) in the synthesis of pradofloxacin.
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creator | BERWE, Mathias DIETZEL, Antje FEY, Peter LONGERICH, Markus WIRTHS, Joerg WISCHNAT, Raif |
description | In step A), ≥30 to ≤40 mol of acetic acid, ≥0.3 to ≤1 mol of sulfuric acid and ≥0.9 to ≤2.5 mol of water are used per mole of compounds of the formula (II). The method is particularly suitable for the synthesis of the intermediate (I) in the synthesis of pradofloxacin. |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS |
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