PCSK9 ANTAGONIST COMPOUNDS

where A, X, R1, and R2 are as defined herein, which compounds have properties for antagonizing PCSK9. Also described are pharmaceutical formulations comprising the compounds of Formula I or their salts, and methods of treating cardiovascular disease and conditions related to PCSK9 activity, e.g. ath...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Wood, Harold B, Liu, Jian, Lo, Michael Man-Chu, Ding, Fa-Xiang, Josien, Hubert, Tucker, Thomas Joseph, Guo, Liangqin, Walji, Abbas
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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